Results of voxelwise comparison of FA on the white matter skeleton (green) with TBSS. Areas of significantly reduced FA in cases are indicated by the colour bar (p < 0.05, TFCE corrected), and include the fornix, corpus callosum, anterior and posterior limbs of the internal capsule bilaterally, and the cingulum bilaterally. These are overlaid on the MNI standard template. Labels indicate some major white matter tracts and regions. Abbreviations are as follows: anterior thalamic radiation (ATR), corpus callosum (CC), external capsule (EC), internal capsule (IC), inferior fronto-occipital fasciculus (IFOF), inferior longitudinal fasciculus (ILF), superior longitudinal fasciculus (SLF), uncinate fasciculus (UF). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)