Age, median (range) |
6.9 (6.0–7.9) |
7.0 (6.1–7.9) |
0.5555 |
7.0 (6.0–7.8) |
7.0 (6.1–7.8) |
0.5428 |
Sex, male/female |
18/15 |
19/17 |
0.8894 |
12/10 |
16/16 |
0.7526 |
Social Grade, median (range) |
C1 (A–E) |
B (A–D) |
0.1568 |
C1 (A–D) |
B (A–D) |
0.0924 |
Index of Multiple Deprivation, median (range) |
7 (1–10) |
7 (2–10) |
0.5211 |
7 (1–10) |
7 (2–10) |
0.8174 |
FSIQ, median (range) |
93 (62–115) |
108 (75–137) |
<0.0001 |
98 (62–114) |
108 (75–137) |
0.0010 |
Perceptual Reasoning, median (range) |
90 (67–123) |
108 (84–145) |
<0.0001 |
91 (67–110) |
108 (84–145) |
<0.0001 |
Processing Speed, median (range) |
97 (68–136) |
106 (68–141) |
0.0787 |
98.5 (75–136) |
106 (68–141) |
0.1221 |
Verbal Comprehension, median (range) |
98 (73–126) |
109 (81–126) |
0.0012 |
98 (73–126) |
109 (81–126) |
0.0114 |
Working Memory, median (range) |
97 (62–116) |
105.5 (77–135) |
0.0076 |
94 (62–116) |
105.5 (77–135) |
0.0290 |
|
Neonatal MRI Assessment |
BGT, median (range) |
0 (0–2) |
– |
– |
0 (0–1) |
– |
– |
WM, median (range) |
1 (0–3) |
– |
– |
1 (0–3) |
– |
– |
PLIC, median (range) |
0 (0–2) |
– |
– |
0 (0–1) |
– |
– |
|
Perinatal Clinical Information |
Mode of delivery, vaginal/instrumental/emergency caesarean in labour/emergency caesarean not in labour |
11/8/10/4 |
– |
– |
8/6/7/1 |
– |
– |
Assisted ventilation at 10 min of age, yes/no |
24/9 |
– |
– |
17/5 |
– |
– |
Cardiac compressions required, yes/no |
13/20 |
– |
– |
8/14 |
– |
– |
Apgar score at 10 min of age, median (range) |
6 (0–10) |
– |
– |
5 (0–10) |
– |
– |
Worst pH within 1 h of birth, median (range) |
6.98 (6.70–7.25) |
– |
– |
6.98 (6.77–7.25) |
– |
– |
Worst base excess within 1 h of birth, median (range) |
−16.0 (−31.0 to −4.8) |
– |
– |
−16.1 (−31.0 to −4.8) |
– |
– |
Grade of encephalopathy: moderate, n (%) |
25 (75.8) |
– |
– |
18 (81.8) |
– |
– |
Grade of encephalopathy: severe, n (%) |
8 (24.2) |
– |
– |
4 (18.2) |
– |
– |
aEEG abnormalities prior to TH: moderate, n (%) |
30 (90.9) |
– |
– |
20 (90.9) |
– |
– |
aEEG abnormalities prior to TH: severe, n (%) |
3 (9.1) |
– |
– |
2 (9.1) |
– |
– |