mRNAs related to neuronal arborization, spine stability and density, among predicted and validated targets of differentially expressed miRNAs in female and male Emx1-Nr3c1−/−mice. (A) Chord diagram representing the predicted interaction of differentially expressed miRNAs (colored arc) with mRNAs in female Emx1-Nr3c1−/− mice (gray arc). (B) Chord diagram representing the involvement of the mRNAs described above in the KEGG biological pathways enriched in female Emx1-Nr3c1−/− mice, with transcripts involved in spine and dendrite dynamics (gray arc) (Koleske, 2013; Forrest et al., 2018) (Table S5). (C) Chord diagram representing the predicted interaction of differentially expressed miRNAs (colored arc) with mRNAs in male Emx1-Nr3c1−/− mice. (D) Chord diagram representing the involvement of mRNAs described above in the KEEG biological pathways enriched in male Emx1-Nr3c1−/− mice, with transcripts involved in spine and dendrite dynamics (gray arc) [(Koleske, 2013; Forrest et al., 2018), Table S5]. The darker gray arc observed for both GSK3B and CAMK2A transcript denotes a rank >70th percentile of the total number of miRNA-mRNA and genes-pathways interactions.