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. 2020 Dec 21;6(3):339–353. doi: 10.1038/s41564-020-00846-z

Fig. 6. RNA interactome inhibitors reduce virus replication.

Fig. 6

a, Top: RT–qPCR measurements of intracellular SARS-CoV-2 RNA at 24 h post-infection in Calu3 cells after inhibitor treatment. Inhibitors were used at the indicated concentrations (left to right). Values were normalized to 18S rRNA measurements and compared to DMSO-treated cells. Bottom: Infectious viral titres in the supernatants of infected Calu3 cells quantified by plaque assays at 24 h post-infection. b, As in a but for Huh7 cells and at 48 h post-infection. All values are the mean ± s.d. (n = 3 independent infections). P values were determined using an unpaired two-tailed t-test. ***P < 0.001, **P < 0.01, *P < 0.05.