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. Author manuscript; available in PMC: 2022 Feb 10.
Published in final edited form as: J Control Release. 2020 Nov 13;330:1080–1094. doi: 10.1016/j.jconrel.2020.11.013

Figure 5.

Figure 5.

For the treatment plan depicted in Fig. 4A, typical histology images of non-treatment-control (A-C), R848-TSL treated (D-F) and distant (G-I), tumors. H&E images with lower (A, D, G) and higher (B, E, H) magnifications. CD8 antibody-stained images (C, F, I) and CD8 area quantification in tumors (J). Mice received 4 injections of R848-TSLs and 3 injections of αPD-1 in total. The scale bars on the lower magnification images are 2 mm, and the scale bars on the higher magnification images are 200 μm. **, p < 0.01.