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Particle size and zeta potential of the empty liposomes and R848-TSLs. R848 was loaded remotely in TSLs via a 100 mM FeSO4 loading gradient. D/L represents drug to lipid ratio. Data = mean ± SD (n = 3).
| Empty liposome | R848-TSLs | |
|---|---|---|
| Diameter (nm) | 107.1 ± 33.5 | 110.3 ± 19.8 |
| PDI | 0.098 | 0.032 |
| D/L (w/w) | - | 0.09 ± 0.01 |
| Zeta Potential (mv) | −20.3 ± 13.6 | −21.3 ± 10.9 |
