Figure 1.
(a) Overall structure of SIRT6 with Myr-H3K9 (green) peptide and ADPr (magenta) bound (PDB code: 3ZG6). (b) Hydrophobic residues in SIRT6 that accommodate the Myr group.
(a) Overall structure of SIRT6 with Myr-H3K9 (green) peptide and ADPr (magenta) bound (PDB code: 3ZG6). (b) Hydrophobic residues in SIRT6 that accommodate the Myr group.