The role of SIRT6 in various human diseases other than cancer. T2DM, Type 2 diabetes mellitus; OA, osteoarthritis; RA, Rheumatoid arthritis; AD, Alzheimer’s disease; PD, Parkinson’s disease ALD, alcohol-related liver disease; NASH, nonalcoholic steatohepatitis; EAE, experimental autoimmune encephalomyelitis; RP, retinitis pigmentosa; DENV, dengue virus; HBV, hepatitis B virus.