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. Author manuscript; available in PMC: 2021 Jun 4.
Published in final edited form as: Nature. 2020 Dec 4;590(7847):630–634. doi: 10.1038/s41586-020-03041-6

Extended Data Figure 6. CD8+ cells following CD8 depletion and SARS-CoV-2 re-challenge.

Extended Data Figure 6.

Rhesus macaques were infected with SARS-CoV-2 and received 50 mg/kg anti-CD8α mAb, anti-CD8β mAb, or sham mAb at week 7, reflecting day −3 relative to re-challenge. On day 0, all animals were re-challenged with 105 TCID50 SARS-CoV-2. Total CD8+ cells, CD8+CD3+ cells, and CD8+CD3- cells per ul peripheral blood are shown. Days following challenge is shown on the x-axis. Red lines reflect median values.