Extended Data Figure 2. Antibody titers following prophylactic adoptive transfer of IgG prior to SARS-CoV-2 challenge.

(a) Log₁₀ pseudovirus neutralizing antibody (NAb) titers, (b) Log₁₀ S-specific ELISA titers, and (c) Log₁₀ RBD-specific ELISA titers in rhesus macaques following intravenous infusion of 250 mg/kg, 25 mg/kg, 2.5 mg/kg of purified SARS-CoV-2 IgG or sham IgG on day −3. On day 0, all animals were challenged with 10⁵ TCID50 SARS-CoV-2. Days following challenge is shown on the x-axis. Red lines reflect median responses. The number of animals is denoted in each panel and the median line overlaps with data lines.