Table 5.

Sex-specific demographic and clinical characteristics for subgroup stratified by 55 years in COVID-19 patients.

Variables	Age ≤ 55 Y (n = 255)			Age > 55 Y (n = 158)
	Male (n = 149)	Female (n = 106)	P-value	Male (n = 81)	Female (n = 77)	P-value
Age, Median(IQR), y	47 (37, 51)	46 (38, 50)	0.494	66 (61, 71)	66 (62, 73)	0.280
current or ever smoking	5 (3.4)	0 (0)	0.078	13 (16.0)	0 (0)	<0.001
Drinking	6 (4.0)	0 (0)	0.043	9 (11.1)	0 (0)	0.003
Comorbidities
COPD	1 (0.7)	0 (0)	NS	5 (6.2)	1 (1.3)	0.236
DM	7 (4.7)	4 (3.8)	0.720	23 (28.4)	20 (26.0)	0.733
Hypertension	13 (8.7)	6 (5.7)	0.358	57 (70.4)	41 (53.2)	0.027
Heart disease	3 (2.0)	2 (1.9)	0.943	12 (14.8)	9 (11.7)	0.563
Kidney disease	1 (0.7)	1 (0.9)	NS	5 (6.2)	3 (3.9)	0.772
Liver disease	2 (1.3)	2 (1.9)	NS	5 (6.2)	3 (3.9)	0.772
Shock	1 (0.7)	0 (0)	NS	7 (8.6)	6 (7.8)	0.846
Tumor	1 (0.7)	1 (0.9)	NS	5 (6.2)	6 (7.8)	0.689
Immune disease	2(1.3)	2(1.9)	NS	2(2.5)	2(2.6)	NS
Symptoms
Fever	141 (94.6)	86 (81.1)	0.001	67 (82.7)	64 (83.1)	0.947
Cough	114 (76.5)	82 (77.4)	0.874	64 (79.0)	60 (77.9)	0.868
Expectoration	56 (37.6)	32 (30.2)	0.221	25 (30.9)	25 (32.5)	0.829
Chest distress	62 (41.6)	43 (40.6)	0.867	48 (59.3)	49 (63.6)	0.572
Chest pain	3 (2.0)	4 (3.8)	0.646	2 (2.5)	4 (5.2)	0.632
Hemoptysis	2 (1.3)	1 (0.9)	NS	2 (2.5)	1 (1.3)	NS
Headache	9 (6.0)	7 (6.6)	0.855	3 (3.7)	4 (5.2)	0.945
Myalgia	15 (10.1)	13 (12.3)	0.580	9 (11.1)	11 (14.3)	0.549
Fatigue	53 (35.6)	32 (30.2)	0.369	30 (37.0)	39 (50.6)	0.085
Gastrointestinal	19 (12.8)	17 (16.0)	0.458	14 (17.3)	18 (23.4)	<0.001
SOFA Score, median (IQR)	1 (0, 2)	1 (0, 2)	0.189	2 (1, 3)	1 (0, 2)	0.009

Data are n (%) unless specified otherwise. P < 0.05 was considered statistically significant. COVID-19, coronavirus disease 2019; IQR, interquartile range; COPD, chronic obstructive pulmonary disease; NS, no significance; DM, diabetes mellitus; SOFA, Sequential Organ Failure Assessment. Bold value means P < 0.05.