Table 1.
Anthropometric and metabolic parameters in groups with and without insulin resistance in the study population.
| Parameters |
IR present
Median (IQR) [HOMA-IR> =2.5] [n = 242] |
IR absent
Median (IQR) [HOMA-IR <2.5] [n = 303] |
Sig. (2-tailed) [Mann-Whitney U Test] | |
|---|---|---|---|---|
| Age (in years) | 11 (9.5–13.5) | 8 (6–10) | <0.001 | |
| Anthropometric parameters | Male sex | |||
| Weight Z-score | 1.41 (1.22–2.4) | 0.91 (0.74–1.38) | <0.01 | |
| Height Z-score | 0.97 (0.66–1.01) | 0.89 (0.68–1.03) | 0.07* | |
| BMI Z-score | 1.43 (1.29–2.3) | 0.88 (0.79–1.56) | <0.01 | |
| WC Z-score | 1.36 (1.02–2.01) | 0.89 (0.63–1.15) | <0.001 | |
| Female sex | ||||
| Weight Z-score | 1.34 (1.19–2.1) | 0.86 (0.74–1.58) | <0.01 | |
| Height Z-score | 0.78 (0.62–1.01) | 0.75 (0.61–1.03) | 0.09* | |
| BMI Z-score | 1.41 (1.24–2.1) | 0.89 (0.77–1.55) | <0.01 | |
| WC Z-score | 1.36 (1.02–2.01) | 0.89 (0.63–1.15) | <0.01 | |
| Hypertension** | Present | 69 (28.5%) | 54 (17.8%) | 0.003 |
| Absent | 173 (71.5%) | 249 (82.2%) | ||
| Metabolic profile | FBS (mg/dL) | 92 (77.5–106.5) | 61 (56.5–74.5) | <0.01 |
| TG (mg/dL) | 145 (96–194) | 82 (77.5–86.5) | <0.01 | |
| HDL (mg/dL) | 40 (32–48) | 100 (81–119) | <0.01 | |
| LDL (mg/dL) | 89 (70–108) | 44 (42.5–45.5) | <0.01 | |
| FPI (mIU/mL) | 16.95 (9.78–24.12) | 7.7 (7.0–8.4) | <0.01 | |
*
P >0.05.
**
Expressed in proportions and analyzed by Chi-square test.
BMI, Body mass index; WC, Waist circumference; HC, Head circumference; BP, Blood pressure; SBP, Systolic BP; DBP, Diastolic BP; FPG, Fasting plasma glucose (normal range: 70–110 mg/dl; coefficient of variation [CV]: 15%), TG, Triglyceride (normal range: 27–185 mg/dl; CV: 19%), HDL, High-density lipoprotein (normal range: 12–86 mg/dl; CV: 19%), LDL, Low-density lipoprotein (normal range: 32–202 mg/dl; CV: 19%), FPI, Fasting plasma insulin (normal range: 3–8 mIU/mL; CV: 21%).