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. 2021 Feb 25;11:4584. doi: 10.1038/s41598-021-83862-1

Figure 1.

Figure 1

Gene arrangement of cagPAI, tfs3, tfs4a, tfs4b, and tfs4c ICE, which were retrieved from H. pylori strain 26,695, Gambia94/24, P12, Shi470, and R036d, respectively. The red color indicates vir homolog T4SS genes in which nucleotide identity is more than 80% to corresponding genes of tfs4b ICE, while horizontal dashed red and dashed gray colors indicate that nucleotide identity was less than 80%, respectively, in a sequence comparison between tfs4b and others (Table 1 and Table S4). The black color indicates the other cag genes of cagPAI (ζ, ε, δ, Z, U, S, Q, P, M, N, I, H, G F, D, B, A). Gray color indicates accessory genes of tfs3 and tfs4 ICE, which included DNA processing genes (xerT and topA) and unknown function genes.