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. 2021 Feb 25;11:4592. doi: 10.1038/s41598-021-84259-w

Table 2.

Effects of intervention and sensitivity analysis.

Outcomes Original analysis Sensitivity analysis
k (n) Participant RR (95% CI; p-value) k (n) Participant RR (95% CI; p-value)
Overall
Endometritis 6 (8) 1707 1.00 (0.80, 1.24; p = 0.970)* 4 (6) 1329 0.98 (0.77, 1.23; p = 0.840)*
Febrile morbidity 3 (4) 744 0.85 (0.43, 1.71; p = 0.650)* 2 (3) 594 0.98 (0.46, 2.06; p = 0.950)*
Incisional SSI 4 (7) 836 0.49 (0.30, 0.78; p = 0.003) 3 (4) 686 0.44 (0.23, 0.86; p = 0.020)*
Subgroup analysis
By placental delivery method
 Endometritis
  Not specified 3 (3) 728 0.80 (0.36, 1.81; p = 0.600)* 2 (2) 578 0.80 (0.36, 1.81; p = 0.600)*
  Manual 3 (3) 604 1.07 (0.82, 1.41; p = 0.610)* 2 (2) 376 1.06 (0.78, 1.45; p = 0.720)*
  Spontaneous 2 (2) 375 0.90 (0.60, 1.33; p = 0.590)* 2 (2) 375 0.90 (0.60, 1.33; p = 0.590)*
 Febrile morbidity
  Not specified 2 (2) 636 0.46 (0.21, 1.00; p = 0.050)* 1 (1) 486 0.49 (0.21, 1.19; p = 0.120)
  Manual 1 (1) 53 1.28 (0.52, 3.19; p = 0.590) 1 (1) 53 1.28 (0.52, 3.19; p = 0.590)
  Spontaneous 1 (1) 55 1.69 (0.56, 5.11; p = 0.360) 1 (1) 55 1.69 (0.56, 5.11; p = 0.360)
 Incisional SSI
  Not specified 3 (5) 728 0.47 (0.29, 0.76; p = 0.002) 2 (2) 578 0.42 (0.25, 0.73; p = 0.002)*
  Manual 1 (1) 53 Not estimable 1 (1) 53 Not estimable
  Spontaneous 1 (1) 55 2.90 (0.12, 68.15; p = 0.510) 1 (1) 55 2.90 (0.12, 68.15; p = 0.510)
By timing of glove change
 Endometritis
  After delivery of fetus 4 (4) 1079 1.01 (0.81, 1.27; p = 0.920)* 2 (2) 751 0.99 (0.78, 1.27; p = 0.950)*
  After delivery of placenta 3 (3) 678 0.80 (0.36, 1.81; p = 0.600)* 2 (2) 578 0.80 (0.36, 1.81; p = 0.600)*
 Febrile morbidity
  After delivery of fetus 2 (2) 208 1.30 (0.67, 2.49; p = 0.440)* 1 (1) 108 1.45 (0.71, 2.93; p = 0.310)
  After delivery of placenta 2 (2) 586 0.45 (0.19, 1.04; p = 0.060)* 1 (1) 486 0.49 (0.21, 1.19; p = 0.120)
 Incisional SSI
  After delivery of fetus 2 (4) 208 0.63 (0.18, 2.22; p = 0.471) 1 (1) 108 2.89 (0.12, 69.47; p = 0.510)*
  After delivery of placenta 3 (4) 678 0.41 (0.25, 0.68; p = 0.001) 2 (2) 578 0.42 (0.25, 0.73; p = 0.002)*

k, number of studies; n, number of effect sizes; RR, risk ratio; CI, confidence interval; SSI, surgical site infection; Manual, manual placental removal method; Spontaneous, spontaneous placental removal method.

*Two-level meta-analysis; †three-level meta-analysis.