Table 2.
Demographic data and clinical parameters of included dengue patients.
| DF | DHF/DSS | |
|---|---|---|
| Number of samples | 48 | 12 |
| M/F ratio | 1.09 | 1.4 |
| Age (mean ± SD) | 8.3 ± 3.8 | 10.1 ± 3.9 |
| Day of fever at inclusion (mean, range) | 3.4 (1–4) | 3.5 (1–4) |
| NS1 + RDT | 34 | 10 |
| DENV RT-qPCR + | 47 | 11 |
| Viral load (RNA copies/ml) (median, IQR) | 3,480 (7.6–16,300,000) | 21.30 (4.4–19,600) |
| DENV-1 | 26 | 3 |
| DENV-2 | 19 | 6 |
| DENV-3 | 0 | 0 |
| DENV-4 | 2 | 1 |
| Secondary infection (%) | 77.1% | 83.3% |
Patients are characterized according to the WHO 1997 criteria. DENV serotype and viral load were determined by RT-qPCR using a standard curve. Viral load is expressed as RNA copies/ml. NS1 positivity was determined by rapid test. Primary or secondary infection was determined based on HIA results on acute and convalescent samples; IQR, interquartile range; NS1, non-structural protein 1; RDT, rapid diagnostic test; DF, dengue fever; DHF, dengue hemorrhagic fever; DSS, dengue shock syndrome.