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. 2021 Feb 25;11:4556. doi: 10.1038/s41598-021-83893-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The effects of osteopathic treatment on regional cerebral flow. The figure shows CBF changes baseline-controlled group differences between treatment and sham group at T2 (referring to the contrast described in the text as (T2_OMT–T0_OMT) vs (T2_SHAM–T0_SHAM)—p < 0.01, false discovery rate (FDR) corrected). L-MFG left middle frontal gyrus, L-pINS left posterior insula, L-LN left lentiform nucleus, L-Cereb(CrI) left cerebellum (Crus I), L-ACC left anterior cingulate cortex, L-SPL left superior parietal lobe, L-PCC left posterior cingulate cortex, L-THAL left thalamus, L-CU left cuneus, R-ACC right anterior cingulate cortex, R-MOFG right mid orbitofrontal gyrus, R-OFC right orbito frontal cortex, R-vplTHAL right ventroposterior lateral thalamus, R-daINS right dorsal anterior insula, R-vaINS right ventral anterior insula.