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. 2021 Feb 25;11:4580. doi: 10.1038/s41598-021-84167-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of the daikenchuto (DKT) on bacterial taxonomic composition. (A) Genus-level classification of bacteria in original fecal inoculums (Feces) and in vitro human colonic microbiota model (KUHIMM) without (−) and with DKT (+ DKT) after 48 h of fermentation. Genera of lower abundance (< 1.0%) and lower similarity (< 97%) were included as Others and Unclassified Bacteria, respectively. Means are shown for nine healthy human subjects. (B) Relative abundances of bacteria related to genus Bifidobacterium. *P < 0.05.