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. 2021 Feb 25;11:4653. doi: 10.1038/s41598-021-84067-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differences in blood flow parameters determined by LSFG among the groups. The percentage differences are shown for four groups with diabetes and compared to the control group. The MBR of the vessels on the ONH in the PDR group is significantly lower than that in the other groups (A). There is no significant difference in the MBR-tissue among the groups (B). The total retinal flow index (TRFI) in the PDR group is significantly lower than the other groups (C).