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. 2021 Feb 25;11:4653. doi: 10.1038/s41598-021-84067-2

Table 4.

Spearman’s rank correlation coefficient of vascular variables with other parameters.

Variables MBR-vessel MBR-tissue TRFI Age Duration of disease DR stage HbA1c T-chol LDL HDL TG SBP DBP OPP HT DL
External diameter (μm) 0.012 − 0.012 0.036 0.121 0.437 0.074 0.020* − 0.136 − 0.007 − 0.205 − 0.107 0.038 − 0.058 − 0.020 0.043 0.100
Lumen diameter (μm) 0.185* 0.085 0.195* 0.110* − 0.012 − 0.288*** 0.117 − 0.128 − 0.020 − 0.140 − 0.156 − 0.033 − 0.092 − 0.038 − 0.149 0.009
Wall thickness (μm) − 0.331*** − 0.172* − 0.362*** 0.042 0.223* 0.587*** 0.024 − 0.100 0.062 − 0.181 − 0.002 0.195* 0.081 0.074 0.400*** 0.116
Wall to lumen ratio − 0.337*** − 0.150 − 0.359*** − 0.023 0.191* 0.643*** − 0.066 − 0.032 0.022 − 0.096 0.097 0.166* 0.105 0.069 0.443*** 0.085

ED: external diameter; LD: lumen diameter; WT: wall thickness; WLR: wall to lumen ratio; T-chol: total cholesterol; LDL: low density lipoprotein; HDL: high density lipoprotein; TG: triglyceride; SBP: systolic blood pressure; DBP: diastolic blood pressure; OPP: ocular perfusion pressure; HT: hypertension; DL: dyslipidemia.

*p < 0.05, **p < 0.01, ***p < 0.001.