Table 2.
Median distance in micros from malignant cell (panCK) phenotypes to tumor associate immune cell (TAIC) phenotypes observed in the malignant pleural mesothelioma cases.
| To TAICs phenotypes | From panCK phenotypes | ||
|---|---|---|---|
| panCK + | panCK + PD-L1- | panCK + PD-L1 + | |
| Median distance in micros | |||
| CD3 + | 33.75 | 33.46 | 30.74 |
| CD3 + PD-L1 + | 110.33 | 115.52 | 84.12 |
| CD3 + PD-1 + | 176.42 | 179.12 | 151.83 |
| CD3 + PD-L1 + PD-1 + | 242.47 | 274.28 | 234.86 |
| CD3 + KI67 + | 120.99 | 120.69 | 121.16 |
| CD3 + KI67 + PD-L1 + | 244.45 | 258.04 | 233.15 |
| CD3 + KI67 + PD-1 + | 267.98 | 287.58 | 284.34 |
| CD3 + KI67 + PD-1 + PD-L1 + | 402.88 | 397.64 | 342.28 |
| CD3 + Foxp3 + CD8- | 265.45 | 259.67 | 258.69 |
| CD3 + Foxp3 + PD-L1 + CD8- | 435.18 | 413.67 | 385.55 |
| CD3 + Foxp3 + PD-1 + CD8- | 347.43 | 329.64 | 365.78 |
| CD3 + CD8 + | 98.29 | 109.78 | 96.00 |
| CD3 + CD8 + PD-L1 + | 232.38 | 269.36 | 191.24 |
| CD3 + CD8 + PD-1 + | 224.94 | 242.95 | 206.57 |
| CD3 + CD8 + PD-1 + PD-L1 + | 367.26 | 369.87 | 275.59 |
| CD3 + CD8 + KI67 + | 249.46 | 285.03 | 258.71 |
| CD3 + CD8 + KI67 + PD-L1 + | 356.88 | 357.77 | 300.75 |
| CD3 + CD8 + KI67 + PD-1 + | 321.10 | 306.60 | 330.10 |
| CD68 + | 47.27 | 46.75 | 42.00 |
| CD68 + KI67 + | 167.88 | 172.60 | 176.39 |
| CD68 + KI67 + PD-L1 + | 261.41 | 278.44 | 245.89 |
| CD68 + PD-L1 + | 161.88 | 171.60 | 129.52 |