Table 1.
Summary of conserved DRACHs distributions among all IAVs HA mRNAs.
| mRNA | Seq no.a | DRACHc | Motif1 | Motif2 | Motif3 | Motif4 | Motif5 | Motif6 | Motif7 | Motif8 | Motif9 | Motif10 | Motif11 | Motif12 | Motif13 | Motif14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| H1N1 PR8b | 1 | 40 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| H1 | 25,576 | 40 | ✓ 95% | ✓ 99% | ✓ 90% | ✓ 85% | ✓ 99% | ✓ 99% | ||||||||
| H2 | 618 | 36 | ✓ 65% | ✓ 95% | ✓ 99% | ✓ 50% | ✓ 99% | ✓ 99% | ✓ 50% | |||||||
| H3 | 23,286 | 42 | ✓ 90% | ✓ 99% | ✓ 90% | ✓ 90% | ✓ 85% | |||||||||
| H4 | 1646 | 51 | ✓ 65% | ✓ 65% | ✓ 99% | ✓ 50% | ✓ 65% | ✓ 85% | ||||||||
| H5 | 5472 | 34 | ✓ 99% | ✓ 75% | ✓ 99% | ✓ 99% | ✓ 75% | |||||||||
| H6 | 1836 | 40 | ✓ 85% | ✓ 75% | ✓ 99% | ✓ 99% | ||||||||||
| H7 | 2237 | 45 | ✓50% | ✓50% | ✓ 95% | ✓50% | ||||||||||
| H8 | 168 | 48 | ✓ 95% | ✓ 85% | ✓ 50% | ✓ 95% | ✓65% | |||||||||
| H9 | 6408 | 43 | ✓ 99% | ✓90% | ✓ 99% | |||||||||||
| H10 | 983 | 45 | ✓95% | ✓50% | ✓ 95% | |||||||||||
| H11 | 781 | 38 | ✓ 50% | ✓ 75% | ✓95% | ✓75% | ✓ 90% | ✓ 90% | ||||||||
| H12 | 337 | 46 | ✓ 90% | ✓ 75% | ✓85% | ✓ 85% | ✓ 95% | |||||||||
| H13 | 409 | 43 | ✓ 95% | |||||||||||||
| H14 | 35 | 44 | ✓ 100% | ✓ 100% | ||||||||||||
| H15 | 16 | 44 | ✓ 50% | |||||||||||||
| H16 | 217 | 41 | ✓ 99% | |||||||||||||
| H17 | 2 | 41 | ✓ 100% | ✓ 100% | ||||||||||||
| H18 | 2 | 47 | ✓ 100% | ✓ 100% |
aThe number of HA sequences listed on IRD and analyzed here in this study.
bThe reference influenza A virus strain utilized in this study, A/Puerto Rico/8/34/Mount Sinai, HA accession no. AF389118.
cThe total number of the possible DRACH motifs located in the consensus sequence in each subtype.