Table 2.
LB hens—weeks 16 to 24: differential metabolite concentrations between weeks 16 and 24 in plasma according to FDR adjusted P-value from t-student’s test.
| Metabolite (µmol/l) | Week 16 | Week 24 | FDR adjusted p-value | t-valuedf |
|---|---|---|---|---|
| Amino acids | ||||
| Tyrosine | 337 ± 9.9 | 172 ± 7.3 | < 0.001 | 13.0918 |
| Threonine | 557 ± 21.2 | 313 ± 20.1 | < 0.001 | 7.7018 |
| Tryptophan | 144 ± 6.4 | 91.8 ± 4.74 | < 0.001 | 6.7718 |
| Histidine | 262 ± 10.2 | 162 ± 16 | < 0.001 | 5.4118 |
| Asparagine | 319 ± 14.1 | 210 ± 15 | < 0.001 | 5.0418 |
| Arginine | 503 ± 10.7 | 389 ± 22.1 | < 0.001 | 4.5618 |
| Glutamine | 1297 ± 35.7 | 883 ± 95.8 | < 0.01 | 3.9818 |
| Alanine | 1156 ± 46.6 | 813 ± 63.7 | < 0.01 | 3.9618 |
| Lysine | 474 ± 31.7 | 310 ± 38.5 | < 0.01 | 3.9618 |
| Proline | 763 ± 29.2 | 592 ± 35.6 | < 0.01 | 3.5818 |
| Biogenic amines | ||||
| Carnosine | 20.3 ± 1.4 | 7.5 ± 0.32 | < 0.001 | 12.7618 |
| trans-4-OH-Pro | 134.4 ± 7.9 | 30.8 ± 3.6 | < 0.001 | 11.4418 |
| Alpha-AAA | 2.1 ± 0.18 | 1.04 ± 0.1 | < 0.001 | 5.3518 |
| Sarcosine | 21.6 ± 0.8 | 12 ± 1.57 | < 0.001 | 5.3218 |
| Spermine | 0.58 ± 0.06 | 0.30 ± 0.01 | < 0.001 | 4.9918 |
| Phospholipids | ||||
| Sum of PCs | 1862 ± 95.8 | 4728 ± 455 | < 0.001 | − 8.5618 |
| Sum of lysoPCs | 54.4 ± 3.38 | 19.3 ± 1.11 | < 0.001 | 10.9118 |
| Sum of SMs | 237.4 ± 11.3 | 160.5 ± 14.2 | < 0.01 | 4.1518 |
Comparison between LB hens at 16 (n = 10) and 24 (n = 10) weeks of age. Values are showed as means ± SEM.
ADMA asymmetric dimethylarginine, Alpha-AAA alpha-aminoadipic acid, Met-SO methionine sulfoxide, PC glycerophosphatidylcholines, SM sphingomyelins.
FDR-adjusted p < 0.05 as significance level was used. t-value indicates the ratio between the difference between and within both groups. Degrees of freedom (df) are shown in the figure as subscript of t-values.