Table 3.
LSL hens—week 16 to 24: differential metabolite concentrations in plasma according to FDR adjusted p-value from t-student’s test.
| Metabolite (µmol/l) | Week 16 | Week 24 | FDR adjusted p-value | t-valuedf |
|---|---|---|---|---|
| Amino acids | ||||
| Threonine | 548 ± 21.6 | 275 ± 24.4 | < 0.001 | 7.7118 |
| Tryptophan | 168 ± 6.3 | 89.3 ± 7.5 | < 0.001 | 7.5818 |
| Asparagine | 347 ± 18.4 | 200 ± 12 | < 0.001 | 7.1118 |
| Histidine | 260 ± 11.4 | 153 ± 10.5 | < 0.001 | 6.5818 |
| Glycine | 1050 ± 32.3 | 689 ± 44.6 | < 0.001 | 6.5418 |
| Alanine | 1090 ± 47.2 | 680 ± 44.7 | < 0.001 | 6.2918 |
| Tyrosine | 289 ± 13.4 | 183 ± 13.1 | < 0.001 | 5.7318 |
| Proline | 898 ± 50.4 | 536 ± 48.4 | < 0.001 | 5.3418 |
| Arginine | 546 ± 18.1 | 408 ± 20.1 | < 0.001 | 5.1618 |
| Aspartate | 72 ± 5.7 | 45 ± 3.5 | < 0.001 | 4.4418 |
| Serine | 1071 ± 29.1 | 868 ± 42.4 | < 0.01 | 3.9618 |
| Valine | 516 ± 21.7 | 348 ± 37.4 | < 0.01 | 3.9618 |
| Methionine | 230 ± 12 | 165 ± 12.3 | < 0.01 | 3.5918 |
| Leucine | 664 ± 29.3 | 516 ± 37.2 | < 0.01 | 3.4018 |
| Glutamine | 1294 ± 42.7 | 1057 ± 65.8 | < 0.01 | 3.2618 |
| Isoleucine | 291 ± 11.7 | 228 ± 20.0 | < 0.05 | 3.0318 |
| Biogenic amines | ||||
| trans-4-OH-Pro | 134 ± 6.4 | 25 ± 1.79 | < 0.001 | 20.4818 |
| Sarcosine | 24 ± 1.3 | 7.9 ± 0.74 | < 0.001 | 10.9218 |
| Carnosine | 26.7 ± 1.2 | 10.2 ± 0.85 | < 0.001 | 10.5318 |
| ADMA | 1.14 ± 0.05 | 0.75 ± 0.03 | < 0.001 | 6.3418 |
| Alpha-AAA | 2.4 ± 0.2 | 1.2 ± 0.1 | < 0.001 | 5.3318 |
| Spermine | 0.62 ± 0.05 | 0.36 ± 0.04 | < 0.001 | 4.5418 |
| Met-SO | 19.9 ± 1 | 13.47 ± 1.32 | < 0.01 | 4.0718 |
| Kynurenine | 0.44 ± 0.07 | 0.18 ± 0.02 | < 0.01 | 3.7318 |
| Taurine | 774 ± 116 | 380 ± 49 | < 0.01 | 3.1718 |
| Putrescine | 0.96 ± 0.1 | 1.69 ± 0.2 | < 0.01 | − 3.1518 |
| Creatinine | 2.95 ± 0.17 | 2.34 ± 0.2 | < 0.05 | 2.4118 |
| Phospholipids | ||||
| Sum of PCs | 1951 ± 65.7 | 4726 ± 393 | < 0.001 | − 9.4418 |
| Sum of lysoPCs | 60.5 ± 4 | 19.9 ± 1 | < 0.001 | 13.7218 |
| Sum of SMs | 246 ± 12.2 | 161 ± 12 | < 0.001 | 4.8818 |
| Hexoses | ||||
| Sum of hexoses | 21,253 ± 998 | 17,995 ± 857 | < 0.05 | 2.5318 |
Comparison between LSL hens at 16 (n = 10) and 24 (n = 10) weeks of age. Values are showed as means ± SEM.
ADMA asymmetric dimethylarginine, Alpha-AAA alpha-aminoadipic acid, Met-SO methionine sulfoxide, PC glycerophosphatidylcholines, SM sphingomyelins.
FDR-adjusted p < 0.05 as significance level was used. t-value indicates the ratio between the difference between and within both groups. Degrees of freedom (df) are shown in the figure as subscript of t-values.