Figure 3.

The simulated mixing of two ensembles, $e_1$ and $e_2$, oscillating in different phases. The phosphorylation level of $e_1$, $\overline{D}(e_1,t)$ (red), and the phosphorylation level of $e_2$, $\overline{D}(e_2,t)$ (blue), are superposed with the phosphorylation level after mixing, $\overline{D}(\mathrm{mix},t)$ (black). $e_1$ and $e_2$ were mixed at $t=0$ designated by a vertical line. (a) $e_1$ at the lowest phosphorylation level and $e_2$ at the highest phosphorylation level were mixed. (b) $e_1$ in the dephosphorylation phase and $e_2$ in the phosphorylation phase were mixed. Parameters are the same as in Fig. 2a–c.