Figure 4.

The simulated mixing of two ensembles oscillating in different phases from A to F. (a) Six phases, A to F, were selected from the simulated curve of the phosphorylation level $\overline{D}(t)$. The simulated results show that the phase of the oscillations of the mixture ensemble are entrained into the phase of gray shaded region. (b) Time when the peaks of $\overline{D}(t)$ appeared after mixing two samples, $e_1$ and $e_2$, is plotted by triangles. White triangles when the same samples were mixed, and filled triangles when samples in different phases were mixed. In each of six panels, the phase of $e_1$ was fixed and the phase of $e_2$ was varied from A to F. In (a) and (b), parameters are the same as in Fig. 3. (c) The plot of the experimental data corresponding to (b). Copied from Ref.¹³ with permission.