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. 2021 Feb 12;9:607341. doi: 10.3389/fcell.2021.607341

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Copyright © 2021 Zeng, Li, Zou, Chen, Li, Li, Ge, Chen and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Partial enlargement of the pathway-act network analysis between PM2.5-100 μg/ml treatment with the control group of the hEROs at 3 weeks. Each node represents a signaling pathway. Arrows represent interactive relationships between two signaling pathways. The size and color of the circle represent the significance of the difference between the groups in the KEGG pathway. The circular red shades represent the clustering coefficients. A darker color indicates more strongly associated pathways. The direction of the arrow represents the upstream and downstream relationship of the path.