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. 2021 Feb 12;11:617472. doi: 10.3389/fneur.2020.617472

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Copyright © 2021 Kossowsky, Schuler, Giulianini, Berde, Reis, Ridker, Buring, Kurth and Chasman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation matrices of aura status and migraine diagnostic symptoms in the study sample. Correlations for aura and the diagnostic symptoms were evaluated in nested samples consisting of full migraineurs (N = 36,105), full and probable migraineurs (N = 54,011), and all migraineurs (N = 69,861). The feature of migraine duration lasting 4–72 h was removed from the full migraineur sample since this feature was present in all migraineurs as imposed by the diagnostic criteria. Unilateral pain, pulsating pain, pain aggravated by physical activity, and pain inhibiting daily activities relate to criterion C of the ICHD diagnostic criteria. Nausea/vomiting, photophobia, and phonophobia relate to criterion D of the ICHD diagnostic criteria.