Table 4.
Univariate and multivariate linear regression analyses.
| Variables | Univariate | Multivariate | VIF | ||
|---|---|---|---|---|---|
| β (95% CI) | P-value | β (95% CI) | P-value | ||
| Male | −4.31 (−7.911, −0.708) | 0.0192 | −7.196 (−10.442, −3.951) | <0.001 | 1.099 |
| Age | 0.046 (−0.072, 0.163) | 0.4453 | N/A | ||
| BMI | 0.9 (0.543, 1.257) | <0.001 | 0.597 (0.223, 0.97) | 0.0019 | 1.390 |
| SBP | 0.161 (0.105, 0.217) | <0.001 | 0.083 (0.028, 0.137) | 0.003 | 1.157 |
| DBP | 0.158 (0.075, 0.24) | <0.001 | – | ||
| Smoking | 1.18 (−2.132, 4.491) | 0.4837 | N/A | ||
| Alcohol use | −0.315 (−4.424, 3.793) | 0.88 | N/A | ||
| HTN | 7.117 (2.58, 11.655) | 0.0022 | – | ||
| DM | −0.788 (−5.511, 3.935) | 0.743 | N/A | ||
| Af | −0.953 (−7.5, 5.593) | 0.7746 | N/A | ||
| Statins | 3.297 (0.225, 6.37) | 0.0355 | – | ||
| CCB | 5.517 (2.342, 8.691) | <0.001 | – | ||
| ACEI/ARB | 6.859 (3.795, 9.922) | <0.001 | – | ||
| Beta-blocker | 7.788 (4.581, 10.996) | <0.001 | – | ||
| MRA | 13.234 (7.755, 18.713) | <0.001 | – | ||
| Folate | 5.222 (1.341, 9.103) | 0.0085 | – | ||
| FPG | 0.345 (−0.655, 1.344) | 0.4976 | N/A | ||
| TC | 0.563 (−1.023, 2.15) | 0.4852 | N/A | ||
| TG | 0.274 (−0.83, 1.379) | 0.6252 | N/A | ||
| HDL-C | 3.198 (−3.95, 10.347) | 0.3792 | N/A | ||
| LDL-C | 1.186 (−0.65, 3.023) | 0.2046 | N/A | ||
| HCY | 0.096 (−0.1, 0.292) | 0.3373 | N/A | ||
| BUN | 2.42 (1.627, 3.213) | <0.001 | 1.332 (0.332, 2.331) | 0.0092 | 1.945 |
| Creatinine | 0.097 (0.064, 0.13) | <0.001 | 0.051 (0.008, 0.095) | 0.0198 | 2.111 |
| Uric acid | 0.022 (0.008, 0.036) | 0.0017 | – | ||
| eGFR | −0.093 (−0.139, −0.048) | <0.001 | – | ||
| AHI | 0.146 (0.075, 0.218) | <0.001 | – | ||
| OAI | 0.152 (0.045, 0.259) | 0.0056 | – | ||
| MSpO2 | −0.994 (−1.464, −0.525) | <0.001 | – | ||
| ODI | 0.147 (0.081, 0.212) | <0.001 | 0.078 (0.009, 0.146) | 0.0263 | 1.410 |
| LSpO2 | −0.258 (−0.39, −0.127) | <0.001 | – | ||
| TS90% | 0.157 (0.079, 0.236) | <0.001 | – | ||
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HTN, hypertension; DM, diabetes mellitus; Af, atrial fibrillation; CCB, calcium channel blocker; ACEI/ARB, angiotensin converting enzyme inhibitor/angiotensin receptor blocker; MRA, mineralocorticoid receptor antagonist; FPG, fasting plasma glucose; TC, total cholesterol; TG, triglyceride; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; HCY, homocysteine; BUN, blood urine nitrogen; eGFR, estimated glomerular filtration rate; AHI, apnea-hypopnea index; OAI, obstructive apnea index; MSpO2, mean nocturnal oxygen saturation; ODI, oxygen desaturation index; LSpO2, lowest oxygen saturation; TS90%, time spent below oxygen saturation of 90%; CI, confidence interval; N/A, non-applicable; VIF, variance inflation factor.