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. 2021 Feb 12;11:585021. doi: 10.3389/fphar.2020.585021

TABLE 5.

The mean ratio of predicted PK parameters of pregnant women at different gestational weeks to that of adult a .

Pregnancy 13 weeks Pregnancy 25 weeks Pregnancy 37 weeks
RCmax_plasma 0.74 0.51 0.50
RAUC_plasma 0.69 0.46 0.44
RCmax_lung 0.76 0.54 0.55
RAUC_lung 0.73 0.51 0.52
a

Adults: baseline population, 20–50 years old healthy Caucasians.