Figure 2.

Performance of the cohort-derived signatures in the whole cohort and tuberculosis subgroups

(A) Active tuberculosis (n=301) versus other diseases (n=327). (B) Culture-confirmed pulmonary tuberculosis (n=112) versus other diseases (n=112). (C) Highly probable tuberculosis (n=89) versus other diseases (n=89) using signatures 1–3, which were derived from the full all active tuberculosis cohort. (D) Highly probable tuberculosis (n=89) versus other diseases (n=89) using signatures 4–6, derived from the highly probable tuberculosis subgroup. (E) Extrapulmonary tuberculosis (n=164) versus other diseases (n=164). Error bars represent the 95% CI. AUC-ROC=area under the receiver-operating characteristic curve.