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. 2021 Feb 24;8(1):e000578. doi: 10.1136/bmjgast-2020-000578

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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A middle-age patient, with a history of dyslipidaemia, was admitted following an episode of abdominal discomfort, rectal blood loss and a vasovagal syncope. On admission COVID-19-screening came back positive. Subsequent flexible sigmoidoscopy revealed unilateral ulcerations in the left colon with rectal sparing (A, B). Histopathology showed patchy atrophic changes, mucus depletion, signs of regeneration and infiltration by polymorphonuclear neutrophils, typical for an ischaemia-type colitis. COVID-19-antibody-staining was positive on various enterocytes (C, D arrows).