TABLE 2.

Inclusion and exclusion criteria.

Principle	Inclusion criteria	Exclusion criteria
Animals	1. Focal MCAO animal models without restriction on the ischemia duration and reperfusion duration.	1. Animal models with noncerebral ischemia, whole-brain ischemia, and ischemia-nonperfusion.
Interventions	2. The PNS (including extracts containing different parts of P. notoginseng) and its preparations have an accurate dosage. 3. The concomitant medication of PNS with certain Chinese medicinal ingredients or therapeutic methods.	2. Intervention drugs of P. notoginseng, non-PNS ingredients of P. notoginseng, P. notoginseng prescription without accurate dose, etc.
Comparators	4. Studies with a control group and data should be extracted if a positive group existed.	3. Experimental design without a control group.
Outcomes	5. Outcomes with NDS measured according to Longa et al. (1989) criteria. Under the premise, the other outcome data should be extracted, including CIV and biochemical indicators.	4. Outcomes without NDS measured according to Longa et al. (1989) criteria, only CIV measurements, physiological or biochemical outcomes of treatment.
Study designs	6. Randomized controlled studies with at least seven experimental animals in each group	5. Each group with seven sample sizes below.
Others	/	6. Case reports, clinical trial studies, abstracts, editorials, reviews, conference abstracts, duplication data, and incomplete text.