Table 2. Characteristics of patients screened for Candida auris, and national cohort patients, with medical records linked to the Case Mix Programme database, England, 2017–2018.
Patient characteristics |
Screened cohorta
n = 881 |
National cohortb,c
n = 162,695 |
p value |
||
---|---|---|---|---|---|
n | % | n | % | ||
Age (years; mean, SD) | 59.0 | 17.7 | 60.9 | 18.0 | 0.001d |
Sex | |||||
Female | 357 | 40.5 | 73,050 | 44.9 | 0.009 |
Male | 524 | 59.5 | 89,645 | 55.1 | |
Ethnicity | |||||
White | 561 | 63.7 | 143,047 | 87.9 | < 0.001e |
Mixed | 4 | 0.5 | 975 | 0.6 | |
Asian | 145 | 16.5 | 6,335 | 3.9 | |
Black | 80 | 9.1 | 4,120 | 2.5 | |
Other | 49 | 5.6 | 2,409 | 1.5 | |
Not stated | 42 | 4.8 | 5,809 | 3.6 | |
Residency | |||||
Non-UK residentf | 3 | 0.3 | 681 | 0.4 | 0.74e |
Severe conditions in medical historyg | |||||
Severe liver disease | 26 | 3.0 | 4,413 | 2.7 | 0.66e |
Very severe cardiovascular disease | 25 | 2.9 | 2,715 | 1.7 | 0.007e |
Severe respiratory disease | 32 | 3.7 | 3,860 | 2.4 | 0.014e |
End-stage renal failure | 56 | 6.4 | 3,559 | 2.2 | < 0.001e |
Haematological malignancy | 34 | 3.9 | 3,244 | 2.0 | < 0.001e |
Metastatic disease | 25 | 2.9 | 5,740 | 3.5 | 0.27e |
Immunocompromised | 99 | 11.3 | 12,767 | 7.9 | < 0.001e |
Prior dependency | |||||
Able to live without assistance | 623 | 71.1 | 123,133 | 76.0 | < 0.001e |
Some minor/major assistance | 249 | 28.4 | 36,976 | 22.8 | |
Total assistance with all daily activities | 4 | 0.5 | 1,813 | 1.1 |
SD: standard deviation; UK: United Kingdom.
a 881/921 screened patients had records that were successfully linked to the Case Mix Programme database.
b These data derive from the Case Mix Programme database. The Case Mix Programme is the national clinical audit of patient outcomes from adult critical care coordinated by the Intensive Care National Audit and Research Centre (ICNARC). For more information on the representativeness and quality of these data, please contact ICNARC (https://www.icnarc.org/).
c All patients admitted to adult general critical care units between 1 April 2016 and 31 March 2017.
d t-test.
e Chi-squared test.
f Based on 865 patients with a UK postcode or country of residence recorded.
g Based on 876 patients with evidence available to assess past medical history.