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. 2021 Feb 2;18(3):1356. doi: 10.3390/ijerph18031356

Table 2.

Intervention cost components, outcomes, and cost-effectiveness results.

Author Intervention Cost(s) Intermediate
Intervention
Effects(s)
Outcome(s) of Interest Incremental Cost-Effectiveness Ratio (A$2020)
Supermarkets
Ball et al. 2016 [25] Intervention materials
Staff time including overheads
Participant time
Purchase of intervention food products
Participant travel expenses
NA
  • (1)

    F&V purchases

  • (2)

    F&V self-reported intake

No effect on fruit intake
$3.39 (95%CI: NR) per increased serve of vegetables consumed per participant per day
Le et al. 2016 [26] I2 and I3: Staff time including overhead
Participant time
Purchase of intervention food products
Participant travel expenses
Intervention materials
NA
  • (1)

    F&V purchases

  • (2)

    F&V self-reported intake

  • (3)

    Low-calorie carbonated diet beverages, and water purchases

  • (4)

    Low-calorie carbonated diet beverages, and water self-reported intake

I1: No difference in all primary outcomes compared to comparator
I2: $2.52 (95%CI: NR) per increased serve of vegetables purchased per week
$3.29 (95%CI: NR) per increased serve of fruit purchased per week
No difference in beverage purchases and intake.
No difference in vegetable intake.
I3: $12.70 (95%CI: NR) per increased serve of fruit purchased per week.
No difference in vegetable and beverage purchases
No difference in fruit, vegetable, and beverage intake
Cobiac et al. 2010 [32] I1: Intervention materials
Monetary incentives
Modelled F&V intake Modelled DALYs averted I1: $3,863,748 (95%CI: NR) per DALY averted
The intervention resulted in 0.030 (95%CI: −0.34; 0.40) increase in serves of F&V per day (not statistically significant)
Remote community stores
Magnus et al. 2016 [28] I1–6: Price discount
Staff time
Intervention materials
I7–12: Price discount
Staff time
Intervention materials
Participant time
Participant travel expenses
Modelled sodium intake, total energy intake and BMI Modelled DALYs averted I1: $30,110 (95%CI: $18,958; $44,607) per DALY averted
I2: $37,916 (95%CI: $22,304; $56,874) per DALY averted
I3: $76,947 (95%CI: $55,759; $101,481) per DALY averted
I4: $49,067 (95%CI: $36,801; $64,680) per DALY averted
I5: $23,418 (95%CI: dominated *; $535,285) per DALY averted
I6: $40,146 (95%CI: dominated *; $356,857 per DALY averted
I7: $53,529 (95%CI: $40,146; $70,256) per DALY averted
I8: $68,026 (95%CI: $50,183; $88,099) per DALY averted
I9: $105,942 (95%CI: $82,523; $133,821) per DALY averted
I10: $56,874 (95%CI: $44,607; $72,487) per DALY averted
I11: $37,916 (95%CI: dominated *; $791,776) per DALY averted
I12: $42,377 (95%CI: dominated *; $390,312) per DALY averted
Magnus et al. 2018 [27] I1: Price discount
Staff time
Staff travel expenses
Intervention materials
I2: Price discount
Staff time
Staff travel expenses
Intervention materials
Participant time
  • (1)

    Store sales of F&V, water and artificially sweetened soft drinks

  • (2)

    Total weight, energy and sodium of food purchases

  • (3)

    Modelled BMI

Modelled DALYs averted I1 and 2: Increased purchase of F&V and other non-discounted foods resulting in modelled increase in BMI of 2.38 (95%CI: 0.81; 4.62) (I1) or 2.37 (95%CI: 0.78; 4.75) (I2).
During the discount period, the negative impact on DALYs averted was from −21 (95%CI: −28; −15) to −36 (95%CI: −47; −25).
At follow−up, the negative impact on DALY averted was from −48 (95%CI: −60; −36) to −45 (95%CI: −58; −34).
Incremental intervention costs:
I1: $239,672 (95%CI: NR)
I2: $433,368 (95%CI: NR)
Interventions were not cost-effective
Restaurants and fast food stores
Gortmaker et al. 2015 [31] I1: Staff time
Nutrition database accessing fee
Compliance monitoring
Modelled calorie intake Modelled BMI I1: $20.55 (95%CI: −$192.52; $242.47) per BMI unit reduced
Allen et al. 2015 [30] Legislation
Compliance monitoring
Product reformulation
Industry loss profitability
Modelled trans fatty acid intake Modelled deaths from coronary heart disease prevented or postponed I1: 1800 (95%CI: 700; 3400) deaths from coronary heart disease averted or 0.7% reduction.
Total annual costs: $185.44M (95%CI: NR)
Net costs saving (excluding reformulation cost): $109.87M (95%CI: $215.57M; $6.03M)
Net costs saving (including reformulation cost): $0.00M (95%CI: $105.47M; −$103.85M)
I2: 2600 (95%CI: 1200; 4600) deaths from coronary heart disease averted or 1.0% reduction
Total annual costs: $220.67M (95%CI: NR)
Net costs saving (excluding reformulation cost): $174.08M (95%CI: $316.41M; $34.31M)
Net costs saving (including reformulation cost): $28.98M (95%CI: $171.30M; −$110.80M)
Modelled QALYs gained I1: Dominant #
QALY gained: 2100 (95%CI: 700; 3900)
Healthcare cost savings: $26.19M (95%CI: $11.59M; $41.26M)
Averted productivity loss: $36.62M (95%CI: $15.99M; $57.49M)
Informal care savings: $122.62M (95%CI: $54.01M; $192.39M)
I2: Dominant #
QALY gained: 3000 (95%CI: 1100; 5200)
Healthcare cost savings: $35.23M (95%CI: $15.53M; $55.17M)
Averted productivity loss: $50.53M (95%CI: $22.25M; $79.28M)
Informal care savings: $164.11M (95%CI: $72.09M; $257.53M)
School cafeterias
Gortmaker et al. 2015 [31] I2: State and local government: Reimbursements for meals
Kitchen equipment for schools
Compliance monitoring
School costs: Meal
Staff time
I3: School costs:
Staff time to keep records of compliance
Training
Modelled calorie intake Modelled BMI I2: $83.22 (95%CI: −$209.49; $292.06) per BMI unit reduced
I3: $9.58 (95%CI: $3.67; $12.22) per BMI unit reduced
Ladapo et al. 2016 [29] Peer leader activities
School-wide multimedia marketing
School food environment changes
  • (1)

    Portions of F&V served

  • (2)

    Number of snacks sold

  • (1)

    Portions of F&V served

  • (2)

    Number of snacks sold

(1) No intervention effect on portions of vegetables served
$1.88 (95%CI: NR) per additional portion of fruit served during meals
(2) $2.65 (95%CI: NR) per reduced unit of snacks sold
Worksite cafeterias and vending machines
Cobiac et al. 2010 [32] I2: Workshop
Nutrition displays
Cafeteria promotion
Advisory board
Time
I3–5: Workshop
Nutrition displays
Cafeteria promotion
Advisory board
Time
Non-tailored documents
I6: Workshop
Nutrition displays
Cafeteria promotion
Advisory board
Time
Family involvement
I7: Nutrition displays
Cafeteria promotion
Non-tailored documents
Modelled F&V intake DALYs averted I2: $11,436,695 (95%CI: NR) per DALY averted
I3: $1,220,945 (95%CI: NR) per DALY averted
I4: $494,560 (95%CI: NR) per DALY averted
I5: $1,854,599 (95%CI: NR) per DALY averted
I6: $664,565 (95%CI: NR) per DALY averted
I7: $72,639 (95%CI: NR) per DALY averted (50% probability of being cost-effective)

Notes: # intervention resulted in more health benefits and less cost compared to the comparator; * intervention resulted in less health benefits and more cost compared to the comparator; A$: Australian dollar; BMI: body mass index; CI: confidence interval; DALYs: disability-adjusted life years; F&V: fruit and vegetable; GBP: British pound sterling; I: intervention; NR: not reported; QALYs: quality-adjusted life years.