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. 2021 Jan 22;18(3):980. doi: 10.3390/ijerph18030980

Figure 2.

Figure 2

Molecular cascade in antral follicle (A) and oocytes (B) during the process of GVBD and meiotic resumption after LH surge/hCG administration; AMP—3′-5′-cyclic adenosine monophosphate; cAMP—3′-5′-cyclic adenosine monophosphate; cGMP—cyclic guanosine monophosphate; Cdc25B—cell division cycle 25B; eNOS—endothelial nitric oxide sinthase; GC—guanylate cyclase; GVBD—germinal vescicle breakdown; hCG—human chorionic gonadotropin; LH—luteinizing hormone; MPF—M phase-promoting factor—NO: nitric oxide; NOS—nitric oxide synthase; PD3A—phosphodiesterase 3A; PKA—protein kinase A.