Table 5.
The minimum inhibitory concentration (MIC) comparison among J1E4, J53, and the transconjugants.
| Antimicrobials | J1E4 (Donor) | J53Coli (Transconjugates) | J53 (Recept) |
|---|---|---|---|
| Ceftriaxone | >128 | >128 | <1 |
| Meropenem | <1 | <1 | <1 |
| Cephalothin | >16 | >16 | >16 |
| Cefpodoxime | >32 | >32 | 2 |
| Ciprofloxacin | 2 | >2 | <1 |
| Cefotaxime | >64 | >64 | <0.25 |
| Gentamicin | <4 | <4 | <4 |
| Cefotaxime/clavulanic acid | <0.12\4 | <0.12\4 | <0.12\4 |
| Ampicillin | >16 | >16 | <8 |
| Ceftazidime | >128 | 32 | 1 |
| Cefazolin | >16 | >16 | <8 |
| Ceftazidime/clavulanic acid | 0.25\4 | 0.5\4 | 0.5\4 |
| Imipenem | <0.5 | 1 | 1 |
| Piperacillin/tazobactam constant 4 | >64\4 | <4\4 | <4\4 |
| Cefepime | >16 | >16 | <1 |
| Colistin | 4 | 8 | <0.25 |
| Cefoxitin | <4 | 8 | <4 |
The MIC was determined with the microdilution methods. The successful transconjugants gain MDR from the donor strain J1E4 including the resistance of colistin, 3rd generation cephalosporins, and ciprofloxacin.