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. 2021 Feb 25;20:111. doi: 10.1186/s12936-021-03652-y

Table 3.

Distribution of KIR and HLA-C genetic variants at the 3 sites in Uganda

Genetic variants Study sites
Tororo, N = 438 n (%) Jinja, N = 414 n (%) Kanungu, N = 446 n (%)
KIR genes
 2DS2 224 (51.1) 218 (52.7) 228 (51.1)
 2DL2 254 (58.0) 240 (58.0) 254 (57.0)
 2DL3 366 (83.6) 352 (85.0) 380 (85.2)
 2DP1 432 (98.6) 409 (98.8) 442 (99.1)
 2DL1 432 (98.6) 409 (98.8) 441 (98.9)
 3DL1 421 (96.1) 394 (95.2) 439 (98.4)
 3DS1 58 (13.2) 75 (18.1) 34 (7.6)
 2DL5 291 (66.4) 264 (63.8) 255 (57.2)
 2DS5 204 (46.6) 180 (43.5) 148 (33.2)
 2DS3 92 (21.0) 84 (20.3) 111 (24.9)
 2DS1 117 (26.7) 126 (30.4) 88 (19.7)
 2DS4 424 (96.8) 392 (94.7) 438 (98.2)
Tororo, N = 385 n (%) Jinja, N = 392 n (%) Kanungu, N = 433 n (%)
KIR genotypes
 AA 150 (39.0) 133 (33.9) 171 (39.5)
 BX 235 (61.0) 259 (66.1) 262 (60.5)
Tororo, N = 356 n (%) Jinja, N = 168 n (%) Kanungu, N = 405 n (%)
HLA-C allotypes
 C1C1 66 (18.5) 39 (23.2) 75 (18.5)
 C1C2 195 (54.8) 93 (55.4) 202 (49.9)
 C2C2 95 (26.7) 36 (21.4) 128 (31.6)
Tororo, N = 438 n (%) Jinja, N = 414 n (%) Kanungu, N = 446 n (%)
Centromeric KIR region
 CenAA 191 (43.6) 171 (41.3) 190 (42.6)
 CenAB 175 (40.0) 182 (44.0) 192 (43.1)
 CenBB 72 (16.4) 61 (14.7) 64 (14.3)
Tororo, N = 438 n (%) Jinja, N = 413 n (%) Kanungu, N = 446 n (%)
Telomeric KIR region
 TelAA 314 (71.7) 283 (68.5) 356 (79.8)
 TelAB 115 (26.3) 112 (27.1) 83 (18.6)
 TelBB 9 (2.0) 18 (4.4) 7 (1.6)
Tororo, N = 313 n (%) Jinja, N = 152 n (%) Kanungu, N = 393 n (%)
Combinations of KIR haplotypes/HLA-C
 AA/C1C1 21 (6.7) 11 (7.3) 22 (5.6)
 AA/C1C2 62 (19.8) 37 (24.3) 93 (23.7)
 AA/C2C2 37 (11.8) 11 (7.2) 46 (11.7)
 BX/C1C1 36 (11.5) 23 (15.1) 50 (12.7)
 BX/C1C2 109 (34.8) 46 (30.3) 105 (26.7)
 BX/C2C2 48 (15.4) 24 (15.8) 77 (19.6)