Fig. 1.

LASSO logistic regression. The bar of the LASSO logistic regression beta coefficients represents the importance of each feature for the classification task (Fig. 1) (Panel a). The positive beta coefficients of the LASSO (upward bars) reflect a susceptible behaviour of the features to the target COVID-19 disease, whereas the negative coefficients (downward bars) a protective action. The calculated odd ratio of AR short repeats (≤22) is 0.79 i.e. protective. Therefore, the odd ratio of long repeats (≥23) is 1/0.79 = 1.27 i.e. severity. Panel b: Table reporting the averages and the standard deviations of accuracy, precision, sensitivity, specificity, and ROC-AUC scores for the 10-folds of the cross-validation.