Table 1.
Baseline demographic and laboratory data in non-alcoholic fatty liver disease/primary biliary cholangitis and non-alcoholic fatty liver disease alone patients
| Variable (normal values) | NAFLD/PBC (N = 68) | NAFLD (N = 136) | P value | ||||
|---|---|---|---|---|---|---|---|
| Mean ± SD | Range | Median (IQR) | Mean ± SD | Range | Median (IQR) | ||
| Age | 64 ± 12 | 41–95 | 62 (55–73) | 64 ± 11 | 41–88 | 63 (56–74) | 0.86 |
| Female (%) | 91 | 91 | |||||
| Haemoglobin (140–180 g/L) | 131 ± 13 | 94–169 | 131 (123–141) | 134 ± 19 | 90–178 | 135 (126–143) | 0.35 |
| WBC (4.5–11 × 10E9/L) | 6.5 ± 1.9 | 2.6–13.1 | 6.5 (5.1–7.6) | 6.9 ± 2.3 | 3.1–15.9 | 6.45 (5.2–8.4) | 0.16 |
| Platelets (140–440 × 10E9/L) | 261 ± 78 | 90–561 | 272 (199–304) | 242 ± 82 | 47–496 | 233.5 (189–292) | 0.11 |
| Alkaline phosphatase (30–120 U/L) | 284 ± 196 | 43 891 | 207.5 (136–399) | 120 ± 123 | 34–1448 | 103 (77–135) | <0.0001 a |
| GGT (5–38 U/L) | 324 ± 318 | 20–2154 | 263.5 (132–404) | 145 ± 205 | 13–1283 | 79 (44–165) | <0.0001 a |
| Creatinine (35–97 µmol/L) | 71 ± 18 | 43–144 | 69 (58-79) | 73 ± 24 | 41–238 | 68 (58–82) | 0.64 |
| IgA (0.7–3.8 g/L) | 3.1 ± 1.5 | 0.07–7.32 | 2.87 (2.0–3.8) | 3.2 ± 1.7 | 0.77–8.37 | 2.96 (1.9–4.1) | 0.51 |
| IgG (6.9–16.2 g/L) | 15.2 ± 4.0 | 7.6–26.8 | 13.95 (12.2–17.7) | 11.5 ± 3.2 | 0.8–22.5 | 11.4 (9.3–13.6) | 0.0001 |
| IgM (0.6–2.6 g/L) | 3.6 ± 2.0 | 0.79–9.68 | 3.43 (2.0–4.7) | 1.5 ± 1.0 | 0.25–6.69 | 1.22 (0.8–1.7) | 0.0001 |
IgA, immunoglobulin A; IgG, immunoglobulin G; IgM, immunoglobulin M; IQR, interquartile range; NAFLD, non-alcoholic fatty liver disease; PBC, primary biliary cholangitis; WBC, white blood cell count.
Bold indicates significant of P values.
a
Non-parametric test.