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. 2021 Jan 20;13(2):144. doi: 10.3390/v13020144

Table 1.

Baseline demographics of HIV-positive men who have sex with men (MSM) enrolled in the clinical trial.

Variables Total Cohort of
HIV+ MSM (n = 129)
HIV+ MSM
Vaccine
(n = 66)
HIV+ MSM
Placebo
(n = 63)
*p
Age, years; mean (±SD) 38.8 (±10.4) 37.3 (±10.6) 40.5 (±10.02) 0.082
Spanish nationality, n (%) 123 (95.3) 63 (95.5) 60 (95.2) 0.2
University education, n (%) 69 (53.5) 34 (51.5) 35 (55.5) 0.56
Partners in previous 12 months; median (IQR) 1 (1–3.75) 1 (1–3) 1 (1–5) 0.8
Life-time partners; n, median (IQR) 72.5 (20.5–300) 50 (20–300) 100 (45–350) 0.041 *
Years of sexual activity; median (IQR) 19 (10–27) 17 (9–24) 21 (13–27) 0.025 *
Condom use, n (%) 100 (77.5 53 (80.3) 47 (74.6) 0.4
Perianal/genital condylomas at screening, n (%) 40 (31) 20 (30.3) 20 (31.7) 0.86
History of condylomas, n (%) 34 (26.4) 19 (28.8) 15 (23.8) 0.52
Duration of HIV; mean months (IQR) 67.5 (31–123.5) 58 (26–120) 77 (37–138) 0.2
History of AIDS; n (%) 40 (31) 19 (28.8) 21 (33.3) 0.58
CD4 mean nadir; cells/µL (±SD) 335,12 (±210.9) 336 (±227.3) 334.2 (±193.7) 0.96
CD4 mean; cells/µL (±SD) 721.9 (±258.8) 733 (±252.7) 710.4 (±266.6) 0.62
CD8 mean; cells/µL (±SD) 996.2 (±422.04) 999.9 (±463.6) 992.2 (±374.9) 0.98
VL of HIV log10; copies/mL (±SD) 3.72 (±4.84) 3.76 (±4.5) 3.67 (±4.46) 0.8
VL < 50 copies/mL, n (%) 106 (82.2) 53 (80.3) 53 (84.1) 0.57
Virological failure, n (%) 4 (3.3) 1 (1.5) 3 (4.8) 0.29
ART, n (%) 119 (92.2) 60 (90.9) 59 (93.7) 0.745
Median duration of ART; months (IQR) 45 (17–101.25) 42 (17–86) 43 (17–129) 0.42
Number of lines of ART, median (IQR) 1 (1–2) 1 (1–2) 1 (1–2) 0.56
Syphilis treated, n (%) 28 (21.7) 16 (24.2) 12 (19.1) 0.47
Other STD, n (%) 23 (17.8) 11 (16.6) 12 (19.1) 0.72
Latent tuberculosis treated, n (%) 15 (11.6) 5 (7.6) 10 (15.9) 0.14
HCV, n (%) 4 (3.1) 2 (3) 2 (3.2) 1
HBV, n (%) 2 (1.6) 2 (3) 0 (0) 0.49
Smoking, packs/year, median (IQR) 1.9 (0–12.5) 0.2 (0–1) 6,5 (0–18) 0.008 *
Ex-smoking, n (%) 23 (17.8) 10 (15) 13 (20.6) 0.42
Ex-IVDA, n (%) 1 (0.8) 1 (1.5) 0 (0) 0.42
Alcohol (standard units of alcohol; SUA) 0.16 (0–1) 0 (0–1) 0.4 (0–1.4) 0.15

*p: p-value; p < 0.05. ART: antiretroviral therapy. VL: viral load; Ex-IDVA: ex-injection drug venous addiction. * FDR correction for multiple comparisons showed that difference was not statistically significant.