Table 2.
Percentage of abnormality of zebrafish embryo (n = 20)
| Groups | Variation of treatment | Abnormal embryo |
Coagulation | Normal embryo | |
|---|---|---|---|---|---|
| Death | Alive | ||||
| Control groups | Positive control | 10% | 85% | 5% | 0% |
| Cardio edema | 10% | 85% | – | – | |
| Somite malformation | 0% | 55% | – | – | |
| Tail abnormal | 0% | 0% | – | – | |
| Others | 0% | 0% | – | – | |
| Negative control | 0% | 0% | 5% | 95% | |
| SNEDDs extract of Centella asiatica | 20 µg/mL | 0% | 0% | 100% | 0% |
| 10 µg/mL | 5% | 20% | 35% | 40% | |
| Cardio edema | 5% | 10% | – | – | |
| Somite malformation | 0% | 20% | – | – | |
| Tail abnormal | 0% | 10% | – | – | |
| Others | 0% | 0% | – | – | |
| 5 µg/mL | 0% | 0% | 5% | 95% | |
| 2,5 µg/mL | 0% | 0% | 5% | 95% | |
| 1,25 µg/mL | 0% | 0% | 0% | 100% | |
| SNEDDs without extract | 20 µg/mL | 30% | 0% | 65% | 5% |
| Cardio edema | 0% | 0% | – | – | |
| Somite malformation | 0% | 0% | – | – | |
| Tail abnormal | 0% | 0% | – | – | |
| Others | 30% | 0% | – | – | |
| 10 µg/mL | 30% | 15% | 45% | 10% | |
| Cardio edema | 10% | 5% | – | – | |
| Somite malformation | 0% | 15% | – | – | |
| Tail abnormal | 0% | 0% | – | – | |
| Others | 0% | 0% | – | – | |
| 5 µg/mL | 0% | 0% | 15% | 85% | |
| 2,5 µg/mL | 0% | 0% | 5% | 95% | |
| 1,25 µg/mL | 0% | 0% | 10% | 90% | |