Table 3.
Genesets enriched in high-MRPS12-phenotype.
| MSigDB collection | Gene set name | NES | NOM P value | FDR q-value |
| c2.cp.biocarta.v7.0.symbols.gmt | BIOCARTA_G2_PATHWAY | 2.01 | .000 | 0.109 |
| BIOCARTA_CELLCYCLE_PATHWAY | 1.89 | .000 | 0.074 | |
| BIOCARTA_ATRBRCA_PATHWAY | 1.73 | .021 | 0.046 | |
| BIOCARTA_G1_PATHWAY | 1.66 | .012 | 0.071 | |
| BIOCARTA_G1_PATHWAY | 1.84 | .000 | 0.055 | |
| BIOCARTA_ATM_PATHWAY | 1.83 | .000 | 0.052 | |
| BIOCARTA_ATRBRCA_PATHWAY | 1.82 | .000 | 0.054 | |
| BIOCARTA_MCM_PATHWAY | 1.77 | .000 | 0.078 | |
| BIOCARTA_CARM_ER_PATHWAY | 1.74 | .002 | 0.099 | |
| BIOCARTA_EFP_PATHWAY | 1.71 | .010 | 0.123 | |
| BIOCARTA_PITX2_PATHWAY | 1.70 | .014 | 0.120 | |
| BIOCARTA_RACCYCD_PATHWAY | 1.65 | .018 | 0.156 | |
| BIOCARTA_VDR_PATHWAY | 1.65 | .019 | 0.151 | |
| BIOCARTA_IGF1MTOR_PATHWAY | 1.64 | .014 | 0.150 | |
| BIOCARTA_P53_PATHWAY | 1.63 | .006 | 0.154 | |
| h.all.v7.0.symbols.gmt [Hallmarks] | HALLMARK_MTORC1_SIGNALING | 1.91 | .004 | 0.113 |
| HALLMARK_MITOTIC_SPINDLE | 1.90 | .000 | 0.086 | |
| HALLMARK_E2F_TARGETS | 1.88 | .004 | 0.065 | |
| HALLMARK_G2M_CHECKPOINT | 1.88 | .000 | 0.055 | |
| HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 1.86 | .008 | 0.053 | |
| HALLMARK_SPERMATOGENESIS | 1.70 | .006 | 0.116 | |
| HALLMARK_PI3K_AKT_MTOR_SIGNALING | 1.69 | .000 | 0.117 |
†NES = normalized enrichment score, NOM = nominal, FDR: false discovery rate. Gene sets with NOM P value< .05 and FDR q-value < 0.25 were considered significant.