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Hypothetical adhesive impact of the interaction of SARS CoV-2 spike protein to integrins. Spike protein interacting with an activated integrin molecule (top inset) provides a mechanism for adhering to endothelial cells and, potentially, platelets, contributing with fibrin to platelet adhesiveness and aggregation (bottom inset). Integrin drawing based on PDB Molecule of the Month: https://pdb101.rcsb.org/motm/134.
