Table 3.
Association between the MACC1 expression and clinicopathological parameters.
| Variables | Cohort (n) | Patients (n) | OR 95%CI | P | I2 (%) | Pheterogeneity | Model | Begg test | Egger test |
| Age (old/young) | 9 | 1249 | 1.02 (0.81, 1.29) | 0.84 | 0 | .6 | Fixed | 0.47 | 0.05 |
| Differentiation (poor/ well or moderate) | 6 | 762 | 2.23 (1.05, 4.74) | 0.04¶ | 76 | <.01 | Random | 0.13 | 0.15 |
| Tumor size (large/small) | 2 | 264 | 1.16 (0.70, 1.92) | 0.56 | 50 | .16 | Fixed | NA | NA |
| FIGO stage (III+IV/I+II) | 9 | 1249 | 3.53 (2.71, 4.60) | <0.01¶ | 0 | .65 | Fixed | 0.18 | 0.05 |
| Ascites (yes/no) | 2 | 272 | 1.23 (0.27, 5.58) | 0.79 | 81 | .02 | Random | NA | NA |
| LNM (yes/no) | 8 | 1202 | 2.87 (2.19, 3.77) | <0.01¶ | 36 | .14 | Fixed | 0.11 | 0.06 |
CI = confidence interval, FIGO = International Federation of Gynecology and Obstetrics, LNM = lymph node metastasis, MACC1 = metastasis-associated in colon cancer-1, NA = not available, OR = odd ratio.
¶
P < .05 indicating the significant association between MACC1 expression and clinicopathological parameters.