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F-actin correlation pathway diagram. RhoA and ROCK1 were regulatory factors upstream of F-actin. The expression of F-actin was regulated by RhoA/ROCK1/LIMK/coffin or MLC pathway. DnaJA4 may inhibit the RhoA/ROCK1 pathway protein expression. GPCR: G-protein-coupled receptor; MLC: Myosin light chain; ROCK: rho-associated serine/threonine kinase.
