Table 3.

Summary of gene set enrichment analysis results.

Entity	Reactome Pathway Name	Size	ES	NES	p-Value	FDR q-Value
Genes	Glucuronidation	15	−0.84	−2.13	<0.001	<0.001
	Chondroitin sulfate dermatan sulfate metabolism	42	−0.57	−1.76	0.002	0.088
	Gap junction trafficking	25	−0.59	−1.65	0.002	0.228
	G β: γ signalling through PI3Kgamma	24	−0.59	−1.65	0.003	0.191
	Activation of kainate receptors upon glutamate binding	29	−0.55	−1.60	0.008	0.236
	Immunoregulatory interactions between a lymphoid and a non-lymphoid cell	58	0.31	1.49	<0.001	0.246
Promoters	Regulation of β cell development	27	−0.64	−1.92	<0.001	0.022
	Regulation of gene expression in β cells	17	−0.64	−1.75	0.002	0.200
	Immunoregulatory interactions between a lymphoid and a non-lymphoid cell	33	0.53	2.20	<0.001	0.007

Pathways with a false discovery rate (FDR) ≤0.25 are shown. Size, number of pathway genes available for analysis; ES, enrichment score for pathway; NES, normalized enrichment score for pathway.