Figure 1.

Tumour burden in properdin-deficient and wildtype mice. Wildtype (PropWT) and properdin-deficient (PropKO) mice were injected subcutaneously with B16F10 cells. After 14 days, the tumour size was measured by callipers. Values are expressed as mean ± SEM from two independent experiments (a). The weight of tumours was established from three independent experiments (including the ones described in a) and values are expressed as mean ± SEM (b). Quantitative analysis of the luciferase signal emitted from the tumour after injection of substrate 12 days following subcutaneous injection of B16F10-luc cells. Values are expressed as mean ± SEM from two independent experiments (c). Data were analysed by two-tailed Mann–Whitney test.