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. 2021 Feb 26;16(2):e0247776. doi: 10.1371/journal.pone.0247776

Fig 5. Addition of ellagic acid decreases AA-induced glutathione depletion in human lymphocytes.

Fig 5

(A) GSH content significantly decreased in AA-treated human lymphocytes while cotreatment EA (50 μM) with AA obviously increased the GSH content in human lymphocytes. (B) Also, AA significantly increased the GSSG content in human lymphocytes after 4 h of exposure while EA (50 μM) significantly decreased the GSSG content in the presence of AA. All experiments were repeated at least three times. ***p < 0.001: Control versus AA; #p < 0.05, ###p < 0.001: AA + EA versus AA-treated human lymphocytes ANOVA, Tukey’s test.