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. 2021 Feb 16;17(2):e1008683. doi: 10.1371/journal.pcbi.1008683

Fig 9. Pathways for the progression of disease.

Fig 9

Healthy tissue corresponds to cells with low intrinsic bistability and high coupling (top-left). Disease can progress by increasing bistability or decreasing coupling strength or both. See S4 Video for an animated version of this figure.