Fig. 2. A 66-year-old man with chronic hepatitis B.

(A) In the arterial phase of Gd-EOB-MRI, there was a 1.4-cm isoenhancing observation (arrow) in segment 8 of the liver. This observation (arrow) presented washout on (B) the portal venous phase, which was inconclusive for a diagnosis of HCC. On CEUS, (C) a 1.6-cm APHE observation (arrow) was noted with mild washout at 87 seconds after contrast agent injection (D, arrow). This observation was concluded to reflect HCC, based on dynamic computed tomography images (APHE with portal washout) and elevated alpha fetoprotein level. APHE = arterial phase hyperenhancement